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ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4⁺ T cell pathogenicity durin...

ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4⁺ T cell pathogenicity durin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5748192

ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4⁺ T cell pathogenicity during CNS inflammation

About this item

Full title

ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4⁺ T cell pathogenicity during CNS inflammation

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (52), p.E11228-E11237

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Although reactivation and accumulation of autoreactive CD4⁺ T cells within the CNS are considered to play a key role in the pathogenesis of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), the mechanisms of how these cells recognize their target organ and induce sustained inflammation are incompletely u...

Alternative Titles

Full title

ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4⁺ T cell pathogenicity during CNS inflammation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5748192

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5748192

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1713664114

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