A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The self-propagation of misfolded conformations of tau underlies neurodegenerative diseases, including Alzheimer's. There is considerable interest in discovering the minimal sequence and active conformational nucleus that defines this self-propagating event. The microtubule-binding region, spanning residues 244–372, reproduces much of the aggregati...
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Full title
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5759337
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5759337
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/nchem.2754
