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Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5766540

Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

About this item

Full title

Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-01, Vol.8 (1), p.574-11, Article 574

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Neurodegenerative diseases (NDD) are typically associated with neuron loss in nervous system areas. Interventions with related death mechanisms may ameliorate NDD progression. Oxidative stress plays an important role in NDD cell death routines. However, tert-butylhydroperoxide (t-BHP), a widely used oxidative stress stimulus, induces neural cell de...

Alternative Titles

Full title

Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5766540

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5766540

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-18935-1

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