Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis
Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis
About this item
Full title
Author / Creator
Wang, Jian , Zhou, Fangzheng , Li, Zhenyu , Mei, Hong , Wang, Ye , Ma, Hong , Shi, Liangliang , Huang, Ai , Zhang, Tao , Lin, Zhenyu and Wu, Gang
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Radiation-induced lung injury has restricted radiotherapy for thoracic cancer. The purpose of this study was to investigate the radioprotective effects of bromodomain and extra terminal (BET) inhibitor JQ1 in a murine model of pulmonary damage. Chest computed tomography (CT) was performed in a rat model after 20 Gy radiation of the right thorax. An...
Alternative Titles
Full title
Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5772369
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5772369
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-19343-9
