Activation of Ca2+-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity i...
Activation of Ca2+-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells
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Author / Creator
Gu, Jie , Dai, Shuya , Liu, Yanmin , Liu, Haitao , Zhang, Yao , Ji, Xingqi , Yu, Feng , Zhou, Yang , Chen, Liang , Tse, William Ka Fai , Wong, Chris Kong Chu , Chen, Binghai and Shi, Haifeng
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Cadmium (Cd), as an extremely toxic metal could accumulate in kidney and induce renal injury. Previous studies have proved that Cd impact on renal cell proliferation, autophagy and apoptosis, but the detoxification drugs and the functional mechanism are still in study. In this study, we used mouse renal tubular epithelial cells (mRTECs) to clarify...
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Full title
Activation of Ca2+-sensing receptor as a protective pathway to reduce Cadmium-induced cytotoxicity in renal proximal tubular cells
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5773512
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5773512
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-19327-9