Affinity purification mass spectrometry analysis of PD-1 uncovers SAP as a new checkpoint inhibitor
Affinity purification mass spectrometry analysis of PD-1 uncovers SAP as a new checkpoint inhibitor
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Programmed cell death-1 (PD-1) is an essential inhibitory receptor in T cells. Antibodies targeting PD-1 elicit durable clinical responses in patients with multiple tumor indications. Nevertheless, a significant proportion of patients do not respond to anti–PD-1 treatment, and a better understanding of the signaling pathways downstream of PD-1 coul...
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Full title
Affinity purification mass spectrometry analysis of PD-1 uncovers SAP as a new checkpoint inhibitor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776966
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5776966
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1710437115
