A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors B...
A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet
About this item
Full title
Author / Creator
Xin, Annie , Masson, Frederick , Liao, Yang , Preston, Simon , Guan, Tianxia , Gloury, Renee , Olshansky, Moshe , Lin, Jian-Xin , Li, Peng , Speed, Terence P , Smyth, Gordon K , Ernst, Matthias , Leonard, Warren J , Pellegrini, Marc , Kaech, Susan M , Nutt, Stephen L , Shi, Wei , Belz, Gabrielle T and Kallies, Axel
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
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Scope and Contents
Contents
Using genetic approaches and transcriptional profiling, Kallies and colleagues reveal a common program of effector CD8
+
T cell differentiation that is regulated by the cooperation of IL-2 and IL-12 signaling and the combined activities of the transcriptional regulators Blimp-1 and T-bet.
T cell responses are guided by cytokines that induc...
Alternative Titles
Full title
A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5779087
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5779087
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3410
