AMPK: guardian of metabolism and mitochondrial homeostasis
AMPK: guardian of metabolism and mitochondrial homeostasis
About this item
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Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Key Points
AMP-activated protein kinase (AMPK) is a highly conserved sensor of low intracellular ATP levels that is rapidly activated after nearly all mitochondrial stresses, even those that do not disrupt the mitochondrial membrane potential.
Upon changes in the ATP-to-AMP ratio, AMPK is activated and phosphorylates downstream targets to red...
Alternative Titles
Full title
AMPK: guardian of metabolism and mitochondrial homeostasis
Authors, Artists and Contributors
Author / Creator
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5780224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5780224
Other Identifiers
ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm.2017.95
