PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression
PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression
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Author / Creator
Tang, Haidong , Liang, Yong , Anders, Robert A , Taube, Janis M , Qiu, Xiangyan , Mulgaonkar, Aditi , Liu, Xin , Harrington, Susan M , Guo, Jingya , Xin, Yangchun , Xiong, Yahong , Nham, Kien , Silvers, William , Hao, Guiyang , Sun, Xiankai , Chen, Mingyi , Hannan, Raquibul , Qiao, Jian , Dong, Haidong , Peng, Hua and Fu, Yang-Xin
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Programmed death-ligand 1 (PD-L1) expression on tumor cells is essential for T cell impairment, and PD-L1 blockade therapy has shown unprecedented durable responses in several clinical studies. Although higher expression of PD-L1 on tumor cells is associated with a better immune response after Ab blockade, some PD-L1-negative patients also respond...
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Full title
PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5785245
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5785245
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI96061
