In silico profiling of systemic effects of drugs to predict unexpected interactions
In silico profiling of systemic effects of drugs to predict unexpected interactions
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Identifying unexpected drug interactions is an essential step in drug development. Most studies focus on predicting whether a drug pair interacts or is effective on a certain disease without considering the mechanism of action (MoA). Here, we introduce a novel method to infer effects and interactions of drug pairs with MoA based on the profiling of...
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Full title
In silico profiling of systemic effects of drugs to predict unexpected interactions
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5785495
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5785495
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-19614-5