Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell respo...
Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell responses
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The B-lymphotropic Epstein–Barr virus (EBV), pandemic in humans, is rapidly controlled on initial infection by T cell surveillance; thereafter, the virus establishes a lifelong latent infection in the host. If surveillance fails, fatal lymphoproliferation and lymphomagenesis ensue. The initial T cell response consists of predominantly CD8⁺ cytotoxi...
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Full title
Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell responses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5789919
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5789919
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1713607115