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Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell respo...

Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell respo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5789919

Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell responses

About this item

Full title

Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell responses

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (4), p.E686-E695

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The B-lymphotropic Epstein–Barr virus (EBV), pandemic in humans, is rapidly controlled on initial infection by T cell surveillance; thereafter, the virus establishes a lifelong latent infection in the host. If surveillance fails, fatal lymphoproliferation and lymphomagenesis ensue. The initial T cell response consists of predominantly CD8⁺ cytotoxi...

Alternative Titles

Full title

Signaling by the Epstein–Barr virus LMP1 protein induces potent cytotoxic CD4⁺ and CD8⁺ T cell responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5789919

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5789919

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1713607115

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