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Panton-Valentine Leukocidin associated with S. aureus osteomyelitis activates platelets via neutroph...

Panton-Valentine Leukocidin associated with S. aureus osteomyelitis activates platelets via neutroph...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5794969

Panton-Valentine Leukocidin associated with S. aureus osteomyelitis activates platelets via neutrophil secretion products

About this item

Full title

Panton-Valentine Leukocidin associated with S. aureus osteomyelitis activates platelets via neutrophil secretion products

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-02, Vol.8 (1), p.2185-15, Article 2185

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Globalization and migration promote the spread of Panton-Valentine leukocidin (PVL)-positive
Staphylococcus aureus
strains. The toxin PVL is linked to the development of thrombosis in association with osteomyelitis. The mechanisms by which PVL drives thrombosis development are however still unknown. We demonstrate that PVL-damaged neutrophils...

Alternative Titles

Full title

Panton-Valentine Leukocidin associated with S. aureus osteomyelitis activates platelets via neutrophil secretion products

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5794969

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5794969

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-20582-z

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