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Newcastle disease virus co‐expressing interleukin 7 and interleukin 15 modified tumor cells as a vac...

Newcastle disease virus co‐expressing interleukin 7 and interleukin 15 modified tumor cells as a vac...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5797827

Newcastle disease virus co‐expressing interleukin 7 and interleukin 15 modified tumor cells as a vaccine for cancer immunotherapy

About this item

Full title

Newcastle disease virus co‐expressing interleukin 7 and interleukin 15 modified tumor cells as a vaccine for cancer immunotherapy

Publisher

England: John Wiley & Sons, Inc

Journal title

Cancer science, 2018-02, Vol.109 (2), p.279-288

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Interleukin 15 (IL15) and IL7 are two cytokines essential for T cell development and homeostasis. In order to improve the antitumor activity by Newcastle disease virus (NDV)‐modified tumor vaccine, we generated a recombinant NDV co‐expressing IL15 and IL7 (LX/IL(15+7)) through incorporation of a 2A self‐processing peptide into IL15 and IL7 using re...

Alternative Titles

Full title

Newcastle disease virus co‐expressing interleukin 7 and interleukin 15 modified tumor cells as a vaccine for cancer immunotherapy

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5797827

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5797827

Other Identifiers

ISSN

1347-9032

E-ISSN

1349-7006

DOI

10.1111/cas.13468

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