Cryo-EM structure of human ATR-ATRIP complex
Cryo-EM structure of human ATR-ATRIP complex
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Author / Creator
Rao, Qinhui , Liu, Mengjie , Tian, Yuan , Wu, Zihan , Hao, Yuhan , Song, Lei , Qin, Zhaoyu , Ding, Chen , Wang, Hong-Wei , Wang, Jiawei and Xu, Yanhui
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
ATR （ataxia telangiectasia-mutated and Rad3-related） protein kinase and ATRIP （ATR-interacting protein） form a complex and play a critical role in response to replication stress and DNA damage. Here, we determined the cryo-electron microscopy （EM） structure of the human ATR-ATRIP complex at 4.7 ~ resolution and built an atomic model of the C-termin...
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Full title
Cryo-EM structure of human ATR-ATRIP complex
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5799817
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5799817
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2017.158
