Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve
Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Reactive oxygen species (ROS) modify proteins and lipids leading to deleterious outcomes. Thus, maintaining their homeostatic levels is vital. This study highlights the endogenous role of LXRs (LXRα and β) in the regulation of oxidative stress in peripheral nerves. We report that the genetic ablation of both LXR isoforms in mice (LXRdKO) provokes s...
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Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5802790
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5802790
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-20980-3