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Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve

Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5802790

Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve

About this item

Full title

Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-02, Vol.8 (1), p.2524-13, Article 2524

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Reactive oxygen species (ROS) modify proteins and lipids leading to deleterious outcomes. Thus, maintaining their homeostatic levels is vital. This study highlights the endogenous role of LXRs (LXRα and β) in the regulation of oxidative stress in peripheral nerves. We report that the genetic ablation of both LXR isoforms in mice (LXRdKO) provokes s...

Alternative Titles

Full title

Liver X Receptor exerts a protective effect against the oxidative stress in the peripheral nerve

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5802790

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5802790

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-20980-3

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