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Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5811607

Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

About this item

Full title

Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-02, Vol.8 (1), p.2871-14, Article 2871

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Here we describe a method for fabricating a primary human Small Intestine-on-a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies. The primary epithelial cells are expanded as 3D organoids, dissociated, and cultured on a porous membrane within a microfluidic device with human intestinal microvascu...

Alternative Titles

Full title

Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5811607

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5811607

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-21201-7

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