Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Here we describe a method for fabricating a primary human Small Intestine-on-a-Chip (Intestine Chip) containing epithelial cells isolated from healthy regions of intestinal biopsies. The primary epithelial cells are expanded as 3D organoids, dissociated, and cultured on a porous membrane within a microfluidic device with human intestinal microvascu...
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Full title
Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5811607
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5811607
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-21201-7