DNMT3A in haematological malignancies
DNMT3A in haematological malignancies
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Key Points
DNA methyltransferase 3A (DNMT3A) belongs to a family of highly conserved DNA methyltransferases that catalyse 5-methylcytosine methylation. Regulatory domains of DNMT3A allow interactions with histone methyltransferases and histones to influence gene expression.
DNMT3A is important in embryonic and haematopoietic stem cell (HSC) d...
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Full title
DNMT3A in haematological malignancies
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5814392
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5814392
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc3895