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DNMT3A in haematological malignancies

DNMT3A in haematological malignancies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5814392

DNMT3A in haematological malignancies

About this item

Full title

DNMT3A in haematological malignancies

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Cancer, 2015-03, Vol.15 (3), p.152-165

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
DNA methyltransferase 3A (DNMT3A) belongs to a family of highly conserved DNA methyltransferases that catalyse 5-methylcytosine methylation. Regulatory domains of DNMT3A allow interactions with histone methyltransferases and histones to influence gene expression.
DNMT3A is important in embryonic and haematopoietic stem cell (HSC) d...

Alternative Titles

Full title

DNMT3A in haematological malignancies

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5814392

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5814392

Other Identifiers

ISSN

1474-175X

E-ISSN

1474-1768

DOI

10.1038/nrc3895

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