Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity
Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The sensor RIG-I detects double-stranded RNA derived from RNA viruses. Although RIG-I is also known to have a role in the antiviral response to DNA viruses, physiological RNA species recognized by RIG-I during infection with a DNA virus are largely unknown. Using next-generation RNA sequencing (RNAseq), we found that host-derived RNAs, most promine...
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Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5815369
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5815369
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ISSN
1529-2908,1529-2916
E-ISSN
1529-2916
DOI
10.1038/s41590-017-0005-y
