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Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5815871

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling

About this item

Full title

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2017-05, Vol.545 (7653), p.234-237

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

The authors describe water-soluble surrogate Wnt agonists, with specificity towards some frizzled (FZD) receptors, which can maintain human intestinal organoid cultures and have effects on the mouse liver
in vivo
.
Water-soluble Wnt agonists
Wnt ligands interact with FZDand Lrp5/6-type receptors to influence diverse developmental, homeo...

Alternative Titles

Full title

Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5815871

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5815871

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature22306

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