Redox-based reagents for chemoselective methionine bioconjugation
Redox-based reagents for chemoselective methionine bioconjugation
About this item
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Author / Creator
Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publication information
Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
Cysteine can be specifically functionalized by a myriad of acid-base conjugation strategies for applications ranging from probing protein function to antibody-drug conjugates and proteomics. In contrast, selective ligation to the other sulfur-containing amino acid, methionine, has been precluded by its intrinsically weaker nucleophilicity. Here, we...
Alternative Titles
Full title
Redox-based reagents for chemoselective methionine bioconjugation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5827972
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5827972
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aal3316
