The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell...
The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock
About this item
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Author / Creator
Hopwood, Thomas W. , Hall, Sarah , Begley, Nicola , Forman, Ruth , Brown, Sheila , Vonslow, Ryan , Saer, Ben , Little, Matthew C. , Murphy, Emma A. , Hurst, Rebecca J. , Ray, David W. , MacDonald, Andrew S. , Brass, Andy , Bechtold, David A. , Gibbs, Julie E. , Loudon, Andrew S. and Else, Kathryn J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Resistance to the intestinal parasitic helminth
Trichuris muris
requires T-helper 2 (T
H
2) cellular and associated IgG1 responses, with expulsion typically taking up to 4 weeks in mice. Here, we show that the time-of-day of the initial infection affects efficiency of worm expulsion, with strong T
H
2 bias and early expulsion in m...
Alternative Titles
Full title
The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5830501
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5830501
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-22021-5
