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16 results for Begley,+Nicola

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ArticlesPeer ReviewedFull Text
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action
Author / Creator:Gibbs, Julie ; Ince, Louise ; Matthews, Laura ; Mei, Junjie ; Bell, Thomas ; Yang, Nan ; Saer, Ben ; Begley, Nicola ; Poolman, Toryn ; Pariollaud, Marie ; Farrow, Stuart ; DeMayo, Francesco ; Hussell, Tracy ; Worthen, G Scott ; Ray, David ; Loudon, Andrew
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2014-08, Vol.20 (8), p.919-926
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REVERBa couples the circadian clock to hepatic glucocorticoid action
Author / Creator:Caratti, Giorgio ; Iqbal, Mudassar ; Hunter, Louise ; Kim, Donghwan ; Wang, Ping ; Vonslow, Ryan M. ; Begley, Nicola ; Tetley, Abigail J. ; Woodburn, Joanna L. ; Pariollaud, Marie ; Maidstone, Robert ; Donaldson, Ian J. ; Zhang, Zhenguang ; Ince, Louise M. ; Kitchen, Gareth ; Baxter, Matthew ; Poolman, Toryn M. ; Daniels, Dion A. ; Stirling, David R. ; Brocker, Chad ; Gonzalez, Frank ; Loudon, Andrew S.I. ; Bechtold, David A. ; Rattray, Magnus ; Matthews, Laura C. ; Ray, David W.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4454-4471
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Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock
Author / Creator:Koch, Alex A ; Bagnall, James S ; Smyllie, Nicola J ; Begley, Nicola ; Adamson, Antony D ; Fribourgh, Jennifer L ; Spiller, David G ; Meng, Qing-Jun ; Partch, Carrie L ; Strimmer, Korbinian ; House, Thomas A ; Hastings, Michael H ; Loudon, Andrew SI
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2022-03, Vol.11
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The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia
Author / Creator:Kitchen, Gareth B. ; Cunningham, Peter S. ; Poolman, Toryn M. ; Iqbal, Mudassar ; Maidstone, Robert ; Baxter, Matthew ; Bagnall, James ; Begley, Nicola ; Saer, Ben ; Hussell, Tracy ; Matthews, Laura C. ; Dockrell, David H. ; Durrington, Hannah J. ; Gibbs, Julie E. ; Blaikley, John F. ; Loudon, Andrew S. ; Ray, David W.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (3), p.1543-1551
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Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation
Author / Creator:Pariollaud, Marie ; Gibbs, Julie E. ; Hopwood, Thomas W. ; Brown, Sheila ; Begley, Nicola ; Vonslow, Ryan ; Poolman, Toryn ; Guo, Baoqiang ; Saer, Ben ; Jones, D. Heulyn ; Tellam, James P. ; Bresciani, Stefano ; Tomkinson, Nicholas C.O. ; Wojno-Picon, Justyna ; Cooper, Anthony W.J. ; Daniels, Dion A. ; Trump, Ryan P. ; Grant, Daniel ; Zuercher, William ; Willson, Timothy M. ; MacDonald, Andrew S. ; Bolognese, Brian ; Podolin, Patricia L. ; Sanchez, Yolanda ; Loudon, Andrew S.I. ; Ray, David W.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-06, Vol.128 (6), p.2281-2296
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The circadian clock protein REVERBα inhibits pulmonary fibrosis development
Author / Creator:Cunningham, Peter S. ; Meijer, Peter ; Nazgiewicz, Alicja ; Anderson, Simon G. ; Borthwick, Lee A. ; Bagnall, James ; Kitchen, Gareth B. ; Lodyga, Monika ; Begley, Nicola ; Venkateswaran, Rajamiyer V. ; Shah, Rajesh ; Mercer, Paul F. ; Durrington, Hannah J. ; Henderson, Neil C. ; Piper-Hanley, Karen ; Fisher, Andrew J. ; Chambers, Rachel C. ; Bechtold, David A. ; Gibbs, Julie E. ; Loudon, Andrew S. ; Rutter, Martin K. ; Hinz, Boris ; Ray, David W. ; Blaikley, John F.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (2), p.1139-1147
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Circadian clock mechanism driving mammalian photoperiodism
Author / Creator:Wood, S. H. ; Hindle, M. M. ; Mizoro, Y. ; Cheng, Y. ; Saer, B. R. C. ; Miedzinska, K. ; Christian, H. C. ; Begley, N. ; McNeilly, J. ; McNeilly, A. S. ; Meddle, S. L. ; Burt, D. W. ; Loudon, A. S. I.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.4291-15, Article 4291
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The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock
Author / Creator:Hopwood, Thomas W. ; Hall, Sarah ; Begley, Nicola ; Forman, Ruth ; Brown, Sheila ; Vonslow, Ryan ; Saer, Ben ; Little, Matthew C. ; Murphy, Emma A. ; Hurst, Rebecca J. ; Ray, David W. ; MacDonald, Andrew S. ; Brass, Andy ; Bechtold, David A. ; Gibbs, Julie E. ; Loudon, Andrew S. ; Else, Kathryn J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-02, Vol.8 (1), p.3782-13, Article 3782
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ArticlesPeer ReviewedFull Text
REVERBa couples the circadian clock to hepatic glucocorticoid action
Author / Creator:Caratti, Giorgio ; Iqbal, Mudassar ; Hunter, Louise ; Kim, Donghwan ; Wang, Ping ; Vonslow, Ryan M ; Begley, Nicola ; Tetley, Abigail J ; Woodburn, Joanna L ; Pariollaud, Marie ; Maidstone, Robert ; Donaldson, Ian J ; Zhang, Zhenguang ; Ince, Louise M ; Kitchen, Gareth ; Baxter, Matthew ; Poolman, Toryn M ; Daniels, Dion A ; Stirling, David R ; Brocker, Chad ; Gonzalez, Frank ; Loudon, Andrew SI ; Bechtold, David A ; Rattray, Magnus ; Matthews, Laura C ; Ray, David W
Publisher:Ann Arbor: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4454-4471
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ArticlesPeer ReviewedFull Text
Circadian clock component REV-ERB[alpha] controls homeostatic regulation of pulmonary inflammation
Author / Creator:Pariollaud, Marie ; Gibbs, Julie E ; Hopwood, Thomas W ; Brown, Sheila ; Begley, Nicola ; Vonslow, Ryan ; Poolman, Toryn ; Guo, Baoqiang ; Saer, Ben ; Jones, D. Heulyn ; Tellam, James P ; Bresciani, Stefano ; Tomkinson, Nicholas C.O ; Wojno-Picon, Justyna ; Cooper, Anthony W.J ; Daniels, Dion A ; Trump, Ryan P ; Grant, Daniel ; Zuercher, William ; Willson, Timothy M ; MacDonald, Andrew S ; Bolognese, Brian ; Podolin, Patricia L ; Sanchez, Yolanda ; Loudon, Andrew S.I ; Ray, David W
Publisher:American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-06, Vol.128 (6), p.2281
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Circadian clock component REV-ERBá controls homeostatic regulation of pulmonary inflammation
Author / Creator:Pariollaud, Marie ; Gibbs, Julie E ; Hopwood, Thomas W ; Brown, Sheila ; Begley, Nicola ; Vonslow, Ryan ; Poolman, Toryn ; Guo, Baoqiang ; Saer, Ben ; Jones, D Heulyn ; Tellam, James P ; Bresciani, Stefano ; Tomkinson, Nicholas C O ; Wojno-Picon, Justyna ; Cooper, Anthony W J ; Daniels, Dion A ; Trump, Ryan P ; Grant, Daniel ; Zuercher, William ; Willson, Timothy M ; MacDonald, Andrew S ; Bolognese, Brian ; Podolin, Patricia L ; Sanchez, Yolanda ; Loudon, Andrew S I ; Ray, David W
Publisher:Ann Arbor: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-06, Vol.128 (6), p.2281-2296
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ArticlesFull Text
Circadian clock function does not require the histone methyltransferase MLL3
Author / Creator:Baxter, Matthew ; Poolman, Toryn ; Cunningham, Peter ; Hunter, Ann Louise ; Voronkov, Maria ; Kitchen, Gareth B ; Goosey, Laurence ; Begley, Nicola ; Kay, Danielle ; Hespe, Abby ; Maidstone, Robert ; Loudon, Andrew ; Ray, David W
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-12
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ArticlesFull Text
Quantification of circadian interactions and protein abundance defines a mechanism for operational stability of the circadian clock
Author / Creator:Bagnall, James S ; Koch, Alex A ; Smyllie, Nicola J ; Begley, Nicola ; Adamson, Antony ; Fribourgh, Jennifer L ; Spiller, David G ; Qing-Jun, Meng ; Partch, Carrie L ; Strimmer, Korbinian ; House, Thomas A ; Hastings, Michael H ; Loudon, Andrew S I
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2021-08
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ArticlesFull Text
Circadian clock mechanism driving mammalian photoperiodism
Author / Creator:Wood, Shona H ; Hindle, Matthew H ; Mizoro, Yasutaka ; Cheng, Yuanyuan ; Saer, Ben Rc ; Miedzinska, Katarzyna ; Christian, Helen C ; Begley, Nicola ; Mcneilly, Judith ; Mcneilly, Alan S ; Meddle, Simone ; Burt, Dave W ; Andrew Si Loudon
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-05
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ArticlesFull Text
Ezh2 restrains macrophage inflammatory responses, and is critical for neutrophil migration in response to pulmonary infection
Author / Creator:Kitchen, Gareth B ; Hopwood, Tom ; Ramamoorthy, Thanuja G ; Downton, Polly ; Begley, Nicola ; Hussell, Tracy ; Dockrell, David H ; Gibbs, Julie E ; Ray, David W ; Loudon, Andrew S
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-07
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The circadian clock protein REVERBα inhibits pulmonary fibrosis development
Author / Creator:Cunningham, Peter S ; Meijer, Peter ; Nazgiewicz, Alicja ; Anderson, Simon G ; Borthwick, Lee A ; Bagnall, James ; Kitchen, Gareth B ; Lodyga, Monika ; Begley, Nicola ; Venkateswaran, Rajamayier V ; Shah, Rajesh ; Mercer, Paul F ; Durrington, Hannah J ; Henderson, Neil C ; Piper-Hanley, Karen ; Fisher, Andrew J ; Chambers, Rachel C ; Bechtold, David A ; Gibbs, Julie E ; Loudon, Andrew S ; Rutter, Martin K ; Hinz, Boris ; Ray, David W ; Blaikley, John
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-09
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An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action

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REVERBa couples the circadian clock to hepatic glucocorticoid action

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Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock

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The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia

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Circadian clock component REV-ERBα controls homeostatic regulation of pulmonary inflammation

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The circadian clock protein REVERBα inhibits pulmonary fibrosis development

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Circadian clock mechanism driving mammalian photoperiodism

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The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock

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REVERBa couples the circadian clock to hepatic glucocorticoid action

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Circadian clock component REV-ERB[alpha] controls homeostatic regulation of pulmonary inflammation

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Circadian clock component REV-ERBá controls homeostatic regulation of pulmonary inflammation

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Circadian clock function does not require the histone methyltransferase MLL3

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Quantification of circadian interactions and protein abundance defines a mechanism for operational stability of the circadian clock

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Circadian clock mechanism driving mammalian photoperiodism

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Ezh2 restrains macrophage inflammatory responses, and is critical for neutrophil migration in response to pulmonary infection

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The circadian clock protein REVERBα inhibits pulmonary fibrosis development

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