Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone
Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone
About this item
Full title
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
An X-ray structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone reveals an extended binding pocket and indicates structural features that could be used to design drugs that specifically target the D2 receptor.
Dopamine's unusual binding technique
D2 dopamine receptors are the principal targets for antipsych...
Alternative Titles
Full title
Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5843546
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5843546
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature25758
