Association of a Novel Mutation in the Plasmodium falciparum Chloroquine Resistance Transporter With...
Association of a Novel Mutation in the Plasmodium falciparum Chloroquine Resistance Transporter With Decreased Piperaquine Sensitivity
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Full title
Author / Creator
Agrawal, Sonia , Moser, Kara A. , Morton, Lindsay , Cummings, Michael P. , Parihar, Ankita , Dwivedi, Ankit , Shetty, Amol C. , Drabek, Elliott F. , Jacob, Christopher G. , Henrich, Philipp P. , Parobek, Christian M. , Jongsakul, Krisada , Huy, Rekol , Spring, Michele D. , Lanteri, Charlotte A. , Chaorattanakawee, Suwanna , Lon, Chanthap , Fukuda, Mark M. , Saunders, David L. , Fidock, David A. , Lin, Jessica T. , Juliano, Jonathan J. , Plowe, Christopher V. , Silva, Joana C. and Takala-Harrison, Shannon
Publisher
US: Oxford University Press
Journal title
Language
English
Formats
Publication information
Publisher
US: Oxford University Press
Subjects
More information
Scope and Contents
Contents
Background. Amplified copy number in the plasmepsin II/III genes within Plasmodium falciparum has been associated with decreased sensitivity to piperaquine. To examine this association and test whether additional loci might also contribute, we performed a genome-wide association study of ex vivo P. falciparum susceptibility to piperaquine. Methods....
Alternative Titles
Full title
Association of a Novel Mutation in the Plasmodium falciparum Chloroquine Resistance Transporter With Decreased Piperaquine Sensitivity
Authors, Artists and Contributors
Author / Creator
Moser, Kara A.
Morton, Lindsay
Cummings, Michael P.
Parihar, Ankita
Dwivedi, Ankit
Shetty, Amol C.
Drabek, Elliott F.
Jacob, Christopher G.
Henrich, Philipp P.
Parobek, Christian M.
Jongsakul, Krisada
Huy, Rekol
Spring, Michele D.
Lanteri, Charlotte A.
Chaorattanakawee, Suwanna
Lon, Chanthap
Fukuda, Mark M.
Saunders, David L.
Fidock, David A.
Lin, Jessica T.
Juliano, Jonathan J.
Plowe, Christopher V.
Silva, Joana C.
Takala-Harrison, Shannon
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5853219
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5853219
Other Identifiers
ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jix334
