PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT
PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (PFKFB3), a key molecule of glucose metabolism in cytoplasm, has been found in various tumors. Emerging evidence has suggested that PFKFB3 is also located in the nucleus and apparent in regulatory functions other than glycolysis. In this study, we found that PFKFB3 expression i...
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PFKFB3 blockade inhibits hepatocellular carcinoma growth by impairing DNA repair through AKT
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5861039
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5861039
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-018-0435-y
