Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin
Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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In the course of thrombosis, platelets are exposed to a variety of activating stimuli classified as ‘strong’ (e.g. thrombin and collagen) or ‘mild’ (e.g. ADP). In response, activated platelets adhere to injured vasculature, aggregate, and stabilise the three-dimensional fibrin scaffold of the expanding thrombus. Since ‘strong’ stimuli also induce o...
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Full title
Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5876378
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5876378
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-23725-4
