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Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5877524

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

About this item

Full title

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2018-02, Vol.19 (3), p.663

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

Progressive cerebral accumulation of tau aggregates is a defining feature of Alzheimer's disease (AD). A popular theory that seeks to explain the apparent spread of neurofibrillary tangle pathology proposes that aggregated tau is passed from neuron to neuron. Such a templated seeding process requires that the transferred tau contains the microtubul...

Alternative Titles

Full title

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5877524

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5877524

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms19030663

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