Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
About this item
Full title
Author / Creator
Shalapour, Shabnam , Lin, Xue-Jia , Bastian, Ingmar N. , Brain, John , Burt, Alastair D. , Aksenov, Alexander A. , Vrbanac, Alison F. , Li, Weihua , Perkins, Andres , Matsutani, Takaji , Zhong, Zhenyu , Dhar, Debanjan , Navas-Molina, Jose A. , Xu, Jun , Loomba, Rohit , Downes, Michael , Yu, Ruth T. , Evans, Ronald M. , Dorrestein, Pieter C. , Knight, Rob , Benner, Christopher , Anstee, Quentin M. and Karin, Michael
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
IgA
+
B cells expressing programmed death ligand 1 (PD-L1) and interleukin 10 accumulate in the inflamed livers of humans and mice with non-alcoholic fatty liver disease where they promote the progression to hepatocellular carcinoma by limiting the local activation of PD-1-expressing CD8
+
T cells.
The role of adaptive immunity in ea...
Alternative Titles
Full title
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
Authors, Artists and Contributors
Author / Creator
Lin, Xue-Jia
Bastian, Ingmar N.
Brain, John
Burt, Alastair D.
Aksenov, Alexander A.
Vrbanac, Alison F.
Li, Weihua
Perkins, Andres
Matsutani, Takaji
Zhong, Zhenyu
Dhar, Debanjan
Navas-Molina, Jose A.
Xu, Jun
Loomba, Rohit
Downes, Michael
Yu, Ruth T.
Evans, Ronald M.
Dorrestein, Pieter C.
Knight, Rob
Benner, Christopher
Anstee, Quentin M.
Karin, Michael
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5884449
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5884449
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature24302
