Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent respon...
Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Inflammation is an established contributor to disease and the NLRP3 inflammasome is emerging as a potential therapeutic target. A number of small molecule inhibitors of the NLRP3 pathway have been described. Here we analysed the most promising of these inhibitor classes side by side to assess relative potency and selectivity for their respective pu...
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Full title
Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5884858
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5884858
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-24029-3