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Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent respon...

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent respon...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5884858

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses

About this item

Full title

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-04, Vol.8 (1), p.5667-11, Article 5667

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inflammation is an established contributor to disease and the NLRP3 inflammasome is emerging as a potential therapeutic target. A number of small molecule inhibitors of the NLRP3 pathway have been described. Here we analysed the most promising of these inhibitor classes side by side to assess relative potency and selectivity for their respective pu...

Alternative Titles

Full title

Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5884858

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5884858

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-24029-3

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