Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of trea...
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer
About this item
Full title
Author / Creator
Barault, Ludovic , Amatu, Alessio , Siravegna, Giulia , Ponzetti, Agostino , Moran, Sebastian , Cassingena, Andrea , Mussolin, Benedetta , Falcomatà, Chiara , Binder, Alexandra M , Cristiano, Carmen , Oddo, Daniele , Guarrera, Simonetta , Cancelliere, Carlotta , Bustreo, Sara , Bencardino, Katia , Maden, Sean , Vanzati, Alice , Zavattari, Patrizia , Matullo, Giuseppe , Truini, Mauro , Grady, William M , Racca, Patrizia , Michels, Karin B , Siena, Salvatore , Esteller, Manel , Bardelli, Alberto , Sartore-Bianchi, Andrea and Di Nicolantonio, Federica
Publisher
England: BMJ Publishing Group LTD
Journal title
Language
English
Formats
Publication information
Publisher
England: BMJ Publishing Group LTD
Subjects
More information
Scope and Contents
Contents
ObjectiveMutations in cell-free circulating DNA (cfDNA) have been studied for tracking disease relapse in colorectal cancer (CRC). This approach requires personalised assay design due to the lack of universally mutated genes. In contrast, early methylation alterations are restricted to defined genomic loci allowing comprehensive assay design for po...
Alternative Titles
Full title
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer
Authors, Artists and Contributors
Author / Creator
Amatu, Alessio
Siravegna, Giulia
Ponzetti, Agostino
Moran, Sebastian
Cassingena, Andrea
Mussolin, Benedetta
Falcomatà, Chiara
Binder, Alexandra M
Cristiano, Carmen
Oddo, Daniele
Guarrera, Simonetta
Cancelliere, Carlotta
Bustreo, Sara
Bencardino, Katia
Maden, Sean
Vanzati, Alice
Zavattari, Patrizia
Matullo, Giuseppe
Truini, Mauro
Grady, William M
Racca, Patrizia
Michels, Karin B
Siena, Salvatore
Esteller, Manel
Bardelli, Alberto
Sartore-Bianchi, Andrea
Di Nicolantonio, Federica
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5897187
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5897187
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gutjnl-2016-313372
