Asparagine bioavailability governs metastasis in a model of breast cancer
Asparagine bioavailability governs metastasis in a model of breast cancer
About this item
Full title
Author / Creator
Knott, Simon R. V. , Wagenblast, Elvin , Khan, Showkhin , Kim, Sun Y. , Soto, Mar , Wagner, Michel , Turgeon, Marc-Olivier , Fish, Lisa , Erard, Nicolas , Gable, Annika L. , Maceli, Ashley R. , Dickopf, Steffen , Papachristou, Evangelia K. , D’Santos, Clive S. , Carey, Lisa A. , Wilkinson, John E. , Harrell, J. Chuck , Perou, Charles M. , Goodarzi, Hani , Poulogiannis, George and Hannon, Gregory J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
In a mouse model of breast cancer, asparagine bioavailability strongly influences metastasis and this is correlated with the production of proteins that regulate the epithelial-to-mesenchymal transition, which provides at least one potential mechanism for how a single amino acid could regulate metastatic progression.
Tumour spread assisted by as...
Alternative Titles
Full title
Asparagine bioavailability governs metastasis in a model of breast cancer
Authors, Artists and Contributors
Author / Creator
Wagenblast, Elvin
Khan, Showkhin
Kim, Sun Y.
Soto, Mar
Wagner, Michel
Turgeon, Marc-Olivier
Fish, Lisa
Erard, Nicolas
Gable, Annika L.
Maceli, Ashley R.
Dickopf, Steffen
Papachristou, Evangelia K.
D’Santos, Clive S.
Carey, Lisa A.
Wilkinson, John E.
Harrell, J. Chuck
Perou, Charles M.
Goodarzi, Hani
Poulogiannis, George
Hannon, Gregory J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5898613
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5898613
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature25465
