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Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5910063

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

About this item

Full title

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2017-09, Vol.549 (7673), p.476-481

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Stem-cell fate can be influenced by metabolite levels in culture, but it is not known whether physiological variations in metabolite levels in normal tissues regulate stem-cell function
in vivo
. Here we describe a metabolomics method for the analysis of rare cell populations isolated directly from tissues and use it to compare mouse haematop...

Alternative Titles

Full title

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5910063

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5910063

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature23876

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