Ascorbate regulates haematopoietic stem cell function and leukaemogenesis
Ascorbate regulates haematopoietic stem cell function and leukaemogenesis
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Stem-cell fate can be influenced by metabolite levels in culture, but it is not known whether physiological variations in metabolite levels in normal tissues regulate stem-cell function
in vivo
. Here we describe a metabolomics method for the analysis of rare cell populations isolated directly from tissues and use it to compare mouse haematop...
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Full title
Ascorbate regulates haematopoietic stem cell function and leukaemogenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5910063
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5910063
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature23876