Molecular mechanisms of α-synuclein and GBA1 in Parkinson’s disease
Molecular mechanisms of α-synuclein and GBA1 in Parkinson’s disease
About this item
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Author / Creator
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Scope and Contents
Contents
Parkinson’s disease (PD) is a neurodegenerative movement disorder characterized pathologically by the presence of Lewy bodies comprised of insoluble alpha (α)-synuclein. Pathological, clinical and genetic studies demonstrate that mutations in the
GBA1
gene, which encodes the lysosomal enzyme glucocerebrosidase (GCase) that is deficient in Gau...
Alternative Titles
Full title
Molecular mechanisms of α-synuclein and GBA1 in Parkinson’s disease
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5916529
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5916529
Other Identifiers
ISSN
0302-766X
E-ISSN
1432-0878
DOI
10.1007/s00441-017-2704-y
