DNA methylation, through DNMT1, has an essential role in the development of gastrointestinal smooth...
DNA methylation, through DNMT1, has an essential role in the development of gastrointestinal smooth muscle cells and disease
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
DNA methylation is a key epigenetic modification that can regulate gene expression. Genomic DNA hypomethylation is commonly found in many gastrointestinal (GI) diseases. Dysregulated gene expression in GI smooth muscle cells (GI-SMCs) can lead to motility disorders. However, the consequences of genomic DNA hypomethylation within GI-SMCs are still e...
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Full title
DNA methylation, through DNMT1, has an essential role in the development of gastrointestinal smooth muscle cells and disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5920081
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5920081
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-018-0495-z
