Control of vacuole membrane homeostasis by a resident PI-3,5-kinase inhibitor
Control of vacuole membrane homeostasis by a resident PI-3,5-kinase inhibitor
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Lysosomes have an important role in cellular protein and organelle quality control, metabolism, and signaling. On the surface of lysosomes, the PIKfyve/Fab1 complex generates phosphatidylinositol 3,5-bisphosphate, PI-3,5-P₂, which is critical for lysosomal membrane homeostasis during acute osmotic stress and for lysosomal signaling. Here, we identi...
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Full title
Control of vacuole membrane homeostasis by a resident PI-3,5-kinase inhibitor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5939101
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5939101
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1722517115