GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestin...
GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3
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New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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The antimicrobial peptides (AMP) produced by intestinal epithelial cells (IEC) play crucial roles in the regulation of intestinal homeostasis by controlling microbiota. Gut microbiota has been shown to promote IEC expression of RegIIIγ and certain defensins. However, the mechanisms involved are still not completely understood. In this report, we fo...
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GPR43 mediates microbiota metabolite SCFA regulation of antimicrobial peptide expression in intestinal epithelial cells via activation of mTOR and STAT3
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5976519
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5976519
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ISSN
1933-0219
E-ISSN
1935-3456
DOI
10.1038/mi.2017.118
