A single injection of crystallizable fragment domain–modified antibodies elicits durable protection...
A single injection of crystallizable fragment domain–modified antibodies elicits durable protection from SHIV infection
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
In the absence of an effective and safe vaccine against HIV-1, the administration of broadly neutralizing antibodies (bNAbs) represents a logical alternative approach to prevent virus transmission. Here, we introduced two mutations encoding amino acid substitutions (M428L and N434S, collectively referred to as ‘LS’) into the genes encoding the crys...
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Full title
A single injection of crystallizable fragment domain–modified antibodies elicits durable protection from SHIV infection
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5989326
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5989326
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0001-2
