Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
About this item
Full title
Author / Creator
Maude, Shannon L , Laetsch, Theodore W , Buechner, Jochen , Rives, Susana , Boyer, Michael , Bittencourt, Henrique , Bader, Peter , Verneris, Michael R , Stefanski, Heather E , Myers, Gary D , Qayed, Muna , De Moerloose, Barbara , Hiramatsu, Hidefumi , Schlis, Krysta , Davis, Kara L , Martin, Paul L , Nemecek, Eneida R , Yanik, Gregory A , Peters, Christina , Baruchel, Andre , Boissel, Nicolas , Mechinaud, Francoise , Balduzzi, Adriana , Krueger, Joerg , June, Carl H , Levine, Bruce L , Wood, Patricia , Taran, Tetiana , Leung, Mimi , Mueller, Karen T , Zhang, Yiyun , Sen, Kapildeb , Lebwohl, David , Pulsipher, Michael A and Grupp, Stephan A
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
CD19-specific CAR T cells were produced centrally for a global study in young people with relapsed B-cell ALL. The overall remission rate was 81%, and patients with a response were negative for minimal residual disease. High-grade toxic effects were frequent but treatable.
Alternative Titles
Full title
Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia
Authors, Artists and Contributors
Author / Creator
Laetsch, Theodore W
Buechner, Jochen
Rives, Susana
Boyer, Michael
Bittencourt, Henrique
Bader, Peter
Verneris, Michael R
Stefanski, Heather E
Myers, Gary D
Qayed, Muna
De Moerloose, Barbara
Hiramatsu, Hidefumi
Schlis, Krysta
Davis, Kara L
Martin, Paul L
Nemecek, Eneida R
Yanik, Gregory A
Peters, Christina
Baruchel, Andre
Boissel, Nicolas
Mechinaud, Francoise
Balduzzi, Adriana
Krueger, Joerg
June, Carl H
Levine, Bruce L
Wood, Patricia
Taran, Tetiana
Leung, Mimi
Mueller, Karen T
Zhang, Yiyun
Sen, Kapildeb
Lebwohl, David
Pulsipher, Michael A
Grupp, Stephan A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5996391
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5996391
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1709866
