DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
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Author / Creator
Brocks, David , Schmidt, Christopher R , Daskalakis, Michael , Jang, Hyo Sik , Shah, Nakul M , Li, Daofeng , Li, Jing , Zhang, Bo , Hou, Yiran , Laudato, Sara , Lipka, Daniel B , Schott, Johanna , Bierhoff, Holger , Assenov, Yassen , Helf, Monika , Ressnerova, Alzbeta , Islam, Md Saiful , Lindroth, Anders M , Haas, Simon , Essers, Marieke , Imbusch, Charles D , Brors, Benedikt , Oehme, Ina , Witt, Olaf , Lübbert, Michael , Mallm, Jan-Philipp , Rippe, Karsten , Will, Rainer , Weichenhan, Dieter , Stoecklin, Georg , Gerhäuser, Clarissa , Oakes, Christopher C , Wang, Ting and Plass, Christoph
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Christoph Plass and colleagues investigate the transcriptomic and epigenomic changes induced by treatment with inhibitors of DNMT and HDAC in cancer cell lines. They observe large numbers of treatment-induced non-annotated TSSs (TINATs) encoded in long-terminal repeats that are normally repressed in most cell types.
Several mechanisms of action...
Alternative Titles
Full title
DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats
Authors, Artists and Contributors
Author / Creator
Schmidt, Christopher R
Daskalakis, Michael
Jang, Hyo Sik
Shah, Nakul M
Li, Daofeng
Li, Jing
Zhang, Bo
Hou, Yiran
Laudato, Sara
Lipka, Daniel B
Schott, Johanna
Bierhoff, Holger
Assenov, Yassen
Helf, Monika
Ressnerova, Alzbeta
Islam, Md Saiful
Lindroth, Anders M
Haas, Simon
Essers, Marieke
Imbusch, Charles D
Brors, Benedikt
Oehme, Ina
Witt, Olaf
Lübbert, Michael
Mallm, Jan-Philipp
Rippe, Karsten
Will, Rainer
Weichenhan, Dieter
Stoecklin, Georg
Gerhäuser, Clarissa
Oakes, Christopher C
Wang, Ting
Plass, Christoph
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6005702
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6005702
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3889
