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IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected...

IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6010884

IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected mice

About this item

Full title

IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected mice

Publisher

England: John Wiley & Sons, Inc

Journal title

Journal of cellular and molecular medicine, 2018-07, Vol.22 (7), p.3353-3363

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

In schistosomiasis japonica and mansoni, parasite eggs trapped in host liver elicit severe liver granulomatous inflammation that subsequently leads to periportal fibrosis, portal hypertension, haemorrhage or even death. Macrophages are critical for granuloma formation and the development of liver fibrosis during schistosomiasis. However, whether th...

Alternative Titles

Full title

IL‐7 suppresses macrophage autophagy and promotes liver pathology in Schistosoma japonicum‐infected mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6010884

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6010884

Other Identifiers

ISSN

1582-1838

E-ISSN

1582-4934

DOI

10.1111/jcmm.13610

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