Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT...
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells
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Mathew, Nimitha R , Braun, Lukas , O'Sullivan, David , Thomas, Simone , Waterhouse, Miguel , Hanke, Kathrin , Illert, Anna L , Duquesne, Sandra , Weber, Arnim , Tugues, Sonia , Follo, Marie , Claus, Rainer , Lübbert, Michael , Rummelt, Christoph , Bertz, Hartmut , Haag, Johanna , Schmidts, Andrea , Schultheiss, Michael , Bettinger, Dominik , Thimme, Robert , Ullrich, Evelyn , Tanriver, Yakup , Vuong, Giang Lam , Arnold, Renate , Hemmati, Philipp , Wolf, Dominik , Wilhelm, Konrad , Leiber, Christian , Gerull, Sabine , Lengerke, Claudia , Pabst, Thomas , Schroeder, Thomas , Rösler, Wolf , Metzelder, Stephan K , Brummer, Tilman , Hu, Zehan , Dengjel, Joern , Hackanson, Björn , Schmid, Christoph , Holtick, Udo , Scheid, Christof , Spyridonidis, Alexandros , Stölzel, Friedrich , Müller, Lutz P , Sicre-de-Fontbrune, Flore , Ihorst, Gabriele , Ehlert, Jan E , Wagner, Eva-Maria , Cahn, Jean-Yves , Schnell, Jacqueline , Kuchenbauer, Florian , Bunjes, Donald , Richardson, Simon , Gill, Saar , Kröger, Nicolaus , Ayuk, Francis , Vago, Luca , Ciceri, Fabio , Müller, Antonia M , Kondo, Takeshi , Teshima, Takanori , Klaeger, Susan , Kuster, Bernhard , Kim, Dennis (Dong Hwan) , Dörfel, Daniela , Bethge, Wolfgang , Hilgendorf, Inken , Andrieux, Geoffroy , Börries, Melanie , Busch, Hauke , Magenau, John , Reddy, Pavan , Labopin, Myriam , Henden, Andrea S , Hill, Geoffrey R , Kennedy, Glen A , Sarma, Anita , McLornan, Donal , Mufti, Ghulam , Oran, Betul , Rezvani, Katayoun , Shah, Omid , Negrin, Robert S , Nagler, Arnon , Prinz, Marco , Burchert, Andreas , Neubauer, Andreas , Beelen, Dietrich , Mackensen, Andreas , Herr, Wolfgang , Becher, Burkhard , Socié, Gerard , Caligiuri, Michael A , Ruggiero, Eliana , Bonini, Chiara , Häcker, Georg , Duyster, Justus , Pearce, Erika , Blazar, Bruce R and Zeiser, Robert
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Combining the kinase inhibitor sorafenib with allogeneic stem cell transplantation boosts immune responses against a subtype of acute myelogenous leukemia, suggesting potential clinical benefit.
Individuals with acute myeloid leukemia (AML) harboring an internal tandem duplication (ITD) in the gene encoding Fms-related tyrosine kinase 3 (FLT3) w...
Alternative Titles
Full title
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells
Authors, Artists and Contributors
Author / Creator
Braun, Lukas
O'Sullivan, David
Thomas, Simone
Waterhouse, Miguel
Hanke, Kathrin
Illert, Anna L
Duquesne, Sandra
Weber, Arnim
Tugues, Sonia
Follo, Marie
Claus, Rainer
Lübbert, Michael
Rummelt, Christoph
Bertz, Hartmut
Haag, Johanna
Schmidts, Andrea
Schultheiss, Michael
Bettinger, Dominik
Thimme, Robert
Ullrich, Evelyn
Tanriver, Yakup
Vuong, Giang Lam
Arnold, Renate
Hemmati, Philipp
Wolf, Dominik
Wilhelm, Konrad
Leiber, Christian
Gerull, Sabine
Lengerke, Claudia
Pabst, Thomas
Schroeder, Thomas
Rösler, Wolf
Metzelder, Stephan K
Brummer, Tilman
Hu, Zehan
Dengjel, Joern
Hackanson, Björn
Schmid, Christoph
Holtick, Udo
Scheid, Christof
Spyridonidis, Alexandros
Stölzel, Friedrich
Müller, Lutz P
Sicre-de-Fontbrune, Flore
Ihorst, Gabriele
Ehlert, Jan E
Wagner, Eva-Maria
Cahn, Jean-Yves
Schnell, Jacqueline
Kuchenbauer, Florian
Bunjes, Donald
Richardson, Simon
Gill, Saar
Kröger, Nicolaus
Ayuk, Francis
Vago, Luca
Ciceri, Fabio
Müller, Antonia M
Kondo, Takeshi
Teshima, Takanori
Klaeger, Susan
Kuster, Bernhard
Kim, Dennis (Dong Hwan)
Dörfel, Daniela
Bethge, Wolfgang
Hilgendorf, Inken
Andrieux, Geoffroy
Börries, Melanie
Busch, Hauke
Magenau, John
Reddy, Pavan
Labopin, Myriam
Henden, Andrea S
Hill, Geoffrey R
Kennedy, Glen A
Sarma, Anita
McLornan, Donal
Mufti, Ghulam
Oran, Betul
Rezvani, Katayoun
Shah, Omid
Negrin, Robert S
Nagler, Arnon
Prinz, Marco
Burchert, Andreas
Neubauer, Andreas
Beelen, Dietrich
Mackensen, Andreas
Herr, Wolfgang
Becher, Burkhard
Socié, Gerard
Caligiuri, Michael A
Ruggiero, Eliana
Bonini, Chiara
Häcker, Georg
Duyster, Justus
Pearce, Erika
Blazar, Bruce R
Zeiser, Robert
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6029618
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6029618
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.4484
