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Chromothripsis in acute myeloid leukemia: biological features and impact on survival

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Chromothripsis in acute myeloid leukemia: biological features and impact on survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6035145

Chromothripsis in acute myeloid leukemia: biological features and impact on survival

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Publisher

London: Nature Publishing Group UK

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Contents

Chromothripsis is a one-step genome-shattering catastrophe resulting from disruption of one or few chromosomes in multiple fragments and consequent random rejoining and repair. This study defines incidence of chromothripsis in 395 newly diagnosed adult acute myeloid leukemia (AML) patients from three institutions, its impact on survival and its gen...

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Chromothripsis in acute myeloid leukemia: biological features and impact on survival

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Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6035145

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6035145

Other Identifiers

ISSN

0887-6924

E-ISSN

1476-5551

DOI

10.1038/s41375-018-0035-y

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