Acinar cell plasticity and development of pancreatic ductal adenocarcinoma
Acinar cell plasticity and development of pancreatic ductal adenocarcinoma
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Key Points
Adult pancreatic acinar cells show high plasticity that enables a change in their differentiation commitment
Acinar-to-ductal metaplasia (ADM) is a mechanism needed for regeneration after inflammation or injury
ADM is a result of epigenetic silencing of markers of acinar cell identity, activation of drivers of acinar cell dediff...
Alternative Titles
Full title
Acinar cell plasticity and development of pancreatic ductal adenocarcinoma
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6036907
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6036907
Other Identifiers
ISSN
1759-5045,1759-5053
E-ISSN
1759-5053
DOI
10.1038/nrgastro.2017.12
