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Innate immune memory in the brain shapes neurological disease hallmarks

Innate immune memory in the brain shapes neurological disease hallmarks

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6038912

Innate immune memory in the brain shapes neurological disease hallmarks

About this item

Full title

Innate immune memory in the brain shapes neurological disease hallmarks

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2018-04, Vol.556 (7701), p.332-338

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Innate immune memory is a vital mechanism of myeloid cell plasticity that occurs in response to environmental stimuli and alters subsequent immune responses. Two types of immunological imprinting can be distinguished—training and tolerance. These are epigenetically mediated and enhance or suppress subsequent inflammation, respectively. Whether immu...

Alternative Titles

Full title

Innate immune memory in the brain shapes neurological disease hallmarks

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6038912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6038912

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0023-4

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