Catalytic activation of β-arrestin by GPCRs
Catalytic activation of β-arrestin by GPCRs
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
β-arrestins are critical regulator and transducer proteins for G-protein-coupled receptors (GPCRs). β-arrestin is widely believed to be activated by forming a stable and stoichiometric GPCR–β-arrestin scaffold complex, which requires and is driven by the phosphorylated tail of the GPCR. Here we demonstrate a distinct and additional mechanism of β-a...
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Full title
Catalytic activation of β-arrestin by GPCRs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6058965
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6058965
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0079-1
