Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of P...
Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells
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Author / Creator
Zhang, Hong-Wei , Hu, Jin-Jiao , Fu, Ruo-Qiu , Liu, Xin , Zhang, Yan-Hao , Li, Jing , Liu, Lei , Li, Yu-Nong , Deng, Qin , Luo, Qing-Song , Ouyang, Qin and Gao, Ning
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Anticancer activities of flavonoids derived from
Tephroseris kirilowii
(Turcz.) Holub. were evaluated in human cancer cells. We isolated and identified, for the first time, eight flavonoids from
T
.
kirilowii
and found that three of them (IH: isorhamnetin, GN: genkwanin, and Aca: acacetin) inhibited cell proliferation in a variety...
Alternative Titles
Full title
Flavonoids inhibit cell proliferation and induce apoptosis and autophagy through downregulation of PI3Kγ mediated PI3K/AKT/mTOR/p70S6K/ULK signaling pathway in human breast cancer cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6062549
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6062549
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-29308-7
