Metformin reverses established lung fibrosis in a bleomycin model
Metformin reverses established lung fibrosis in a bleomycin model
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Fibrosis is a pathological result of a dysfunctional repair response to tissue injury and occurs in a number of organs, including the lungs
1
. Cellular metabolism regulates tissue repair and remodelling responses to injury
2
–
4
. AMPK is a critical sensor of cellular bioenergetics and controls the switch from anabolic to catabol...
Alternative Titles
Full title
Metformin reverses established lung fibrosis in a bleomycin model
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6081262
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6081262
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-018-0087-6
