Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
About this item
Full title
Author / Creator
Chen, Gang , Huang, Alexander C. , Zhang, Wei , Zhang, Gao , Wu, Min , Xu, Wei , Yu, Zili , Yang, Jiegang , Wang, Beike , Sun, Honghong , Xia, Houfu , Man, Qiwen , Zhong, Wenqun , Antelo, Leonardo F. , Wu, Bin , Xiong, Xuepeng , Liu, Xiaoming , Guan, Lei , Li, Ting , Liu, Shujing , Yang, Ruifeng , Lu, Youtao , Dong, Liyun , McGettigan, Suzanne , Somasundaram, Rajasekharan , Radhakrishnan, Ravi , Mills, Gordon , Lu, Yiling , Kim, Junhyong , Chen, Youhai H. , Dong, Haidong , Zhao, Yifang , Karakousis, Giorgos C. , Mitchell, Tara C. , Schuchter, Lynn M. , Herlyn, Meenhard , Wherry, E. John , Xu, Xiaowei and Guo, Wei
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Tumour cells evade immune surveillance by upregulating the surface expression of programmed death-ligand 1 (PD-L1), which interacts with programmed death-1 (PD-1) receptor on T cells to elicit the immune checkpoint response
1
,
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. Anti-PD-1 antibodies have shown remarkable promise in treating tumours, including metastatic melanoma
2...
Alternative Titles
Full title
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response
Authors, Artists and Contributors
Author / Creator
Huang, Alexander C.
Zhang, Wei
Zhang, Gao
Wu, Min
Xu, Wei
Yu, Zili
Yang, Jiegang
Wang, Beike
Sun, Honghong
Xia, Houfu
Man, Qiwen
Zhong, Wenqun
Antelo, Leonardo F.
Wu, Bin
Xiong, Xuepeng
Liu, Xiaoming
Guan, Lei
Li, Ting
Liu, Shujing
Yang, Ruifeng
Lu, Youtao
Dong, Liyun
McGettigan, Suzanne
Somasundaram, Rajasekharan
Radhakrishnan, Ravi
Mills, Gordon
Lu, Yiling
Kim, Junhyong
Chen, Youhai H.
Dong, Haidong
Zhao, Yifang
Karakousis, Giorgos C.
Mitchell, Tara C.
Schuchter, Lynn M.
Herlyn, Meenhard
Wherry, E. John
Xu, Xiaowei
Guo, Wei
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6095740
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6095740
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-018-0392-8
