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Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6095740

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Publication information

Publisher

London: Nature Publishing Group UK

Subjects

Subjects and topics

More information

Scope and Contents

Contents

Tumour cells evade immune surveillance by upregulating the surface expression of programmed death-ligand 1 (PD-L1), which interacts with programmed death-1 (PD-1) receptor on T cells to elicit the immune checkpoint response
1
,
2
. Anti-PD-1 antibodies have shown remarkable promise in treating tumours, including metastatic melanoma
2...

Alternative Titles

Full title

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6095740

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6095740

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/s41586-018-0392-8

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