Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated tran...
Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Pre-existing anti-adenovirus (Ad) neutralizing antibodies (AdNAbs) are a major barrier in clinical gene therapy using Ad vectors and oncolytic Ads; however, it has not been fully elucidated which Ad capsid protein-specific antibodies are involved in AdNAb-mediated inhibition of Ad infection
in vivo
. In this study, mice possessing antibodies...
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Full title
Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6098129
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6098129
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-30947-z
