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Cation trafficking propels RNA hydrolysis

Cation trafficking propels RNA hydrolysis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6110950

Cation trafficking propels RNA hydrolysis

About this item

Full title

Cation trafficking propels RNA hydrolysis

Publisher

New York: Nature Publishing Group US

Journal title

Nature structural & molecular biology, 2018-08, Vol.25 (8), p.715-721

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Catalysis by members of the RNase H superfamily of enzymes is generally believed to require only two Mg
2+
ions that are coordinated by active-site carboxylates. By examining the catalytic process of
Bacillus halodurans
RNase H1 in crystallo, however, we found that the two canonical Mg
2+
ions and an additional K
+
failed to...

Alternative Titles

Full title

Cation trafficking propels RNA hydrolysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6110950

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6110950

Other Identifiers

ISSN

1545-9993

E-ISSN

1545-9985

DOI

10.1038/s41594-018-0099-4

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